Comparing of Microcoil Localization and Hook Wire Localization for Resectable Pulmonary Small Nodules

Peking University

Status and phase: Unknown; Phase 3

Conditions: Thoracic Surgery

Treatments: Procedure: hookwire localization; Procedure: microcoil localization

Study type: Interventional

Funder types: Other

Identifiers

NCT02908646

2014PHB113

Details and patient eligibility

About

Both of microcoil localization and hookwire localization have been proved as good preoperative CT(computed tomography)-guided techniques to guide VATS resection for the diagnosis of small peripheral pulmonary nodules technique to guide VATS resection for the diagnosis of small peripheral pulmonary nodules. The objective of this study is to determine if microcoil localization for pulmonary nodules can be safer than hookwire localization

Full description

Both of microcoil localization and hookwire localization have been proved as good preoperative CT-guided techniques to guide VATS resection for the diagnosis of small peripheral pulmonary nodules technique to guide VATS(video assisted thoracoscopic surgery) resection for the diagnosis of small peripheral pulmonary nodules. Compared with the commonly used hook wire, the platinum microcoil can be retained in the patients'body and the configuration of which had an effect in reducing the severity of complications. The fibered microcoil may promote blood coagulation of the surrounding lung tissues, block the needle pathway, and decrease the severity of pneumothorax and bleeding caused by the puncture needle, which has been proven in animal experiments. The objective of this study is to determine if microcoil localization for pulmonary nodules can be safer than hookwire localization

Enrollment: 72 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• solid nodules with a diameter ≤1 cm and distance to visceral pleura ≥0.5 cm, -ground-glass nodules,
• part-solid ground-glass nodules, with a solid portion ≤1 cm and distance to the visceral pleura ≥1 cm.
• peripheral nodules amenable to thoracoscopic wedge excision of the nodules.

Exclusion criteria

• Patients combined with pneumothorax.
• Patients combined with pleural effusion.
• Patients with history of hemoptysis.
• Patients with medical condition that the radiologist and surgeon disagree for inclusion.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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72 participants in 2 patient groups, including a placebo group

microcoil

Experimental group

Description:

patients who plan for microcoil localization

Treatment:

Procedure: microcoil localization

hookwire

Placebo Comparator group

Description:

patients who plan for hookwire localization

Treatment:

Procedure: hookwire localization