Comparing Outcome of Thoracocentesis and Pigtail Catheter Drainage in Treatment of Patients With Hepatic Hydrothorax

Sohag University

Status: Enrolling

Conditions: Hepatic Hydrothorax

Treatments: Procedure: Thoracocentasis

Study type: Interventional

Funder types: Other

Identifiers

NCT06319547

Soh-Med-24-02-07MS

Details and patient eligibility

About

Hepatic hydrothorax (HH) is a pleural effusion that develops in a patient with cirrhosis and portal hypertension in the absence of cardiopulmonary disease (Lv et al., 2018). Several factors are known to contribute to the development of effusion; the most accepted mechanism of which is the direct delivery of ascitic fluid from the peritoneal cavity to the pleural cavity by "positive" intra-abdominal pressure and a "negative" intrathoracic pressure of the pleural cavity through microscopic congenital diaphragmatic defects (Han et al., 2022).

Enrollment: 100 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients who met the following inclusion criteria were enrolled:
• Liver cirrhosis (with or without hepatocellular carcinoma).
• Hepatic hydrothorax (bilateral or unilateral).

Exclusion criteria

• patients with a pleural effusion due to a condition other than HH.
• who had a diagnosis of tuberculosis pleurisy, parapneumonic effusion, inflammatory pleuritis, other neoplasms, and congestive heart failure.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 1 patient group

hepatic hydrothorax

Experimental group

Description:

patient with hepatic hydrothorax that develop pleural effusion either unilateral or bilateral

Treatment:

Procedure: Thoracocentasis