Comparing Patients After ESWL Treated With Ureteral Stents Versus Expulsion Therapy With Tamsulosin

Hadassah Medical Center

Status and phase: Unknown; Phase 2

Conditions: Upper Tract Ureterolithiasis

Treatments: Drug: Tamsulosin

Study type: Interventional

Funder types: Other

Identifiers

NCT00478998

890pal- HMO-CTIL

Details and patient eligibility

About

The purpose of this study is to see whether patients undergoing ESWL, for upper tract urinary stones between 1.5-2.0cm, may be treated by expulsion therapy(Tamsulosin) instead of inserting ureteral stents .

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients above 18 yrs of age.
• Single urolithiasis up to 2 cm.
• Kidney/ureters that haven't undergone previous ESWL or stent insertion.
• Normal renal function (creatinine below 100mmo1/1).
• Sterile urine culture.
• Normal CBC, blood electrolytes and coagulation studies.
• Radioopaque stones.

Exclusion criteria

• More than one stone per kidney unit.
• Patients receiving steroids, NSAIDS, calcium channel blockers or alpha blockers on a regular basis.
• Anatomical anomalies or uromechanical obstruction.
• Single kidney.
• Cystinuria.
• Soldiers or pregnant women.
• Patients under 18 year

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind