Comparing Steroid Injections and Platelet Rich Plasma Injections in the Treatment of Plantar Fasciitis

King Hamad University Hospital, Bahrain

Status and phase: Withdrawn; Phase 3; Phase 2

Conditions: Plantar Fasciitis

Treatments: Biological: Platelet rich plasma injection; Drug: Corticosteroid injection (Bupivacaine and Depo Medrol)

Study type: Interventional

Funder types: Other

Identifiers

NCT01957631

AJB88AK

Details and patient eligibility

About

In cases of Plantar Fasciitis not responding to conservative management, minimally invasive techniques may be used. These include platelet rich plasma injections and corticosteroid injections. Corticosteroids have long been used for symptomatic relief. However there are growth factors present in PRP injections that contribute to the healing of the pathology, and not just symptom control.

A single blind, prospective, randomized, comparative, control study will be performed. The study population consists of a total of 80 participants. They will be randomly assigned to receive either a corticosteroid injection, or a platelet rich plasma injection. Data will be collected through questionnaires and ultrasound findings. Patients will have a follow up at 3, 6, 12, and 24 weeks after they receive their injection.

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients aged 18+
• Patients with Plantar Fasciitis for at least 6 months which has not responded to 6 weeks of conservative therapy
• Patients with a visual analogue score (VAS) of more than 5 in the morning
• Patients must be able to understand the informed consent and have the ability to follow up.

Exclusion criteria

• Patients who have had repeated corticosteroid injections within the past 3 months, or have taken a non-steroid anti inflammatory drug during the 1 week prior to receiving an intervention
• BMI > 40
• Patients with a previous foot deformity
• Patients who have had previous foot surgery
• History of anemia (Hb < 7)
• Confirmed diagnosis of neuropathy
• Patients who have the inability to follow up

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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0 participants in 2 patient groups

Corticosteroid injection

Active Comparator group

Description:

Corticosteroid injection

Treatment:

Drug: Corticosteroid injection (Bupivacaine and Depo Medrol)

Platelet rich plasma injection

Experimental group

Description:

Platelet rich plasma injection

Treatment:

Biological: Platelet rich plasma injection