Comparing the Effect of Spinal Bupivacaine Versus Spinal Prilocaine on Maternal Blood Pressure in Cesarean Section

South Valley University

Status: Not yet enrolling

Conditions: Spinal Anesthetics Causing Adverse Effects in Therapeutic Use

Treatments: Drug: Bupivacaine; Drug: Prilocaine

Study type: Interventional

Funder types: Other

Identifiers

NCT06290583

Prilocaine in cesarean section

Details and patient eligibility

About

one of the most common complications associated with spinal anesthesia is hypotension, which can have adverse effects on both the mother and the fetus. The present study compare prilocaine versus bupivacaine in spinal anesthesia on hypotension and there effect on maternal outcomes.

Enrollment: 60 estimated patients

Sex: Female

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Pregnant >36 weeks singleton baby
• American Society of Anesthesiologists (ASA) physical status 2
• Age : between 18 years old and 35 years old

Exclusion criteria

• Pregnant women with cardiac disease and history of psychiatric illness
• Pregnant women who received spinal anesthesia and converted to general anesthesia
• Women who have sensitivity to local anesthetics,
• Women who have Eclampsia, abruption placenta or placenta previa
• Women who have coagulopathy, thrombocytopenia with platelet count less than 80,000/cm3, myasthenia

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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60 participants in 2 patient groups

Group B

Active Comparator group

Description:

Patients will be given spinal anesthesia with bupivacaine (10 mg) added to morphine (100 microgram) and will be diluted with 0.9% saline to the 3 ml final volume to be injected.

Treatment:

Drug: Bupivacaine

Group P

Active Comparator group

Description:

Patients will be given spinal anesthesia with prilocaine (50 mg) added to morphine (100 microgram) and will be diluted with 0.9% saline to the 3 ml final volume to be injected.

Treatment:

Drug: Prilocaine