Comparing the Effect of TAP-catheter and Epidural Catheter on Postoperative Pain After Open Gynecologic Surgery

Aalborg University Hospital

Status: Withdrawn

Conditions: Pain, Postoperative

Treatments: Drug: Ropivacaine bolus in transversus abdominis plane catheter; Drug: Bupivacain-infusion in epidural catheter

Study type: Interventional

Funder types: Other

Identifiers

NCT01760174

N-20120041

Details and patient eligibility

About

This study compares the effect on postoperative pain of bolus administration of ropivacaine in Transversus abdominis plane catheter and continuous bupivacain-infusion in epidural catheters following open gynecologic surgery.The study is double blind. The hypothesis is that the effect of the two modes of pain treatment are equal.

Full description

Patients for open gynecologic surgery will all receive both an epidural catheter and bilateral transversus abdominis plane (:TAP) catheters. After randomization in to two groups the patients receive either 1) intermittent boluses of ropivacaine in the TAP-catheters and isotonic potassium chloride-infusion i the epidural catheters or 2) intermittent isotonic potassium chloride-boluses i the TAP-catheters and bupivacain-infusion in the epidural catheters.

The investigators record pain-score and consumption of opioids in the first 24 hours postoperatively as well as thermoanalgesia at dermatome-levels th10-th12.

The investigators assume that the effect on postoperative pain after open gynecologic surgery is equal in the two groups.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients scheduled for open gynecologic surgery
• acceptance to participate

Exclusion criteria

• allergies to local analgetics
• daily use of strong opioids

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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0 participants in 2 patient groups

Bupivacain-infusion in epidural catheter

Active Comparator group

Description:

Bupivacain-infusion in epidural catheter and intermittent isotonic potassium chloride bolus in transversus abdominis plane catheter.

Treatment:

Drug: Bupivacain-infusion in epidural catheter

Ropivacaine bolus in transversus abdominis plane catheter

Active Comparator group

Description:

Intermittent ropivacaine bolus in bilateral transversus abdominis plane catheter and isotonic potassium chloride infusion in epidural catheter.

Treatment:

Drug: Ropivacaine bolus in transversus abdominis plane catheter