Comparing the Effectiveness of Cyanoacrylate Tissue Adhesives and Conventional Sutures

Melaka Manipal Medical College

Status: Completed

Conditions: Wound Heal

Treatments: Procedure: closure of wound using n- butyl 2-octyl cyanoacrylate tissue adhesive; Procedure: closure of wound using braided silk suture

Study type: Interventional

Funder types: Other

Identifiers

NCT04898816

MMMC/FOD/AR/B8/E C-2020 (08)

Details and patient eligibility

About

This study compares the effectiveness of two materials used for intraoral wound closure after removal of impacted mandibular third molar tooth. One Group received braided black silk suture and the other group received N-butyl 2-octyl cyanoacrylate tissue adhesives.

Full description

Conventional method of wound closure after removal of impacted mandibular molar is by suturing the wound using braided black silk suture and allowing for primary healing. Suturing in the most posterior region of oral cavity is not easy, it requires more time and additional skills as well. Patient has to come for a second visit for removal of suture. Moreover tight sutures may lead to ischemia and necrosis.

Tissue adhesives adopts the idea of sutureless wound closure. They are even sloughed off from the surface of mucosa 7 days after the application.

This study compares the effectiveness of conventional sutures and tissue adhesives in closure of intraoral surgical wounds after removal of mandibular third molar.

Enrollment: 20 patients

Sex: All

Ages: 17+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• patients requiring surgical removal of mesioangular, position A impacted mandibular third molar
• clean incisions approximately 2-3 cms in length which can be approximated
• Healthy (ASAI) or patients with mild systemic disease no functional limitations
• Patients not allergic to the drugs or anesthetic agents used in the surgical protocol

Exclusion criteria

• Patients taking any medications that influences wound healing
• Patients on non steroidal anti inflammatory drugs
• smokers
• uncooperative patients patients allergic to cyanoacrylate

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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20 participants in 2 patient groups

Group A

Experimental group

Description:

Application of cyanoacrylate tissue adhesive over the surgical wound

Treatment:

Procedure: closure of wound using n- butyl 2-octyl cyanoacrylate tissue adhesive

Group B

Active Comparator group

Description:

Suturing the surgical wound using braided black silk

Treatment:

Procedure: closure of wound using braided silk suture