Comparing the Efficacy of Visible Light-Ultraviolet A1 Light Versus Narrowband-Ultraviolet B on Generalized Vitiligo

Henry Ford Health

Status

Terminated

Conditions

Generalized Vitiligo

Treatments

Procedure: Visible Light-Ultraviolet A Light or Narrowband-Ultraviolet B phototherapy

Study type

Interventional

Funder types

Other

Identifiers

NCT05238077

11973

Details and patient eligibility

About

As part of this study, you may have a procedure called phototherapy which involves either VL-UVA or NB-UVB irradiation. NB-UVB phototherapy is not experimental in vitiligo, but use of VL-UVA1 phototherapy in vitiligo is.

The purpose of this pilot study is to determine whether VL-UVA1 or NB-UVB phototherapy more efficiently induces repigmentation in patients with generalized vitiligo.

Enrollment

1 patient

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Subjects ≥ 18 years of age with a diagnosis of generalized vitiligo
Subjects on a stable topical/oral regimen for the past 3 months and continuing on a stable regimen
Subjects able to understand the requirements of the study
Subjects able and willing to sign informed consent

Exclusion criteria

Subjects on photosensitizing medications
Subjects receiving any concurrent phototherapy
Subjects who plan to use tanning parlors or expose themselves to excess sunlight
Subjects with known photosensitivity disorder
Subjects with apparent phototoxicity
Subjects with unstable vitiligo
Subjects currently using bleaching agents
Subjects who are pregnant, lactating, or planning on becoming pregnant
Subjects who in the opinion of the investigator/sub-investigator, are not appropriate candidates for this study