Comparing the Prognosis of Lactate-directed and Goal-directed Therapy in Hyperthermic Intraperitoneal Chemotherapy.

Taipei Medical University

Status: Withdrawn

Conditions: Organ Failure, Multiple

Treatments: Other: Lactate-directed therapy; Other: Goal-directed therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT03933930

N201803039

Details and patient eligibility

About

Hyperthermic intraperitoneal chemotherapy is a major surgery for tumor peritoneal metastasis. For anesthesiologist, the intra-operative fluid control is always a big challenge. We try to compare the prognosis of lactate-directed and goal-directed therapy. We expect to confirm the better prognosis of lactate-directed therapy.

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients receiving hyperthermic intraperitoneal chemotherapy

Exclusion criteria

• Unable to set arterial line Severe liver or renal disease Severe heart disease Unconscious patients

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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0 participants in 2 patient groups

Lactate-directed therapy

Experimental group

Treatment:

Other: Lactate-directed therapy

Other: Goal-directed therapy

Goal-directed therapy

Experimental group

Treatment:

Other: Goal-directed therapy