Comparing Two Different Modes of Ventilation in Pretem Neonates Bilevel VG and PRVC

Ankara City Hospital

Status: Completed

Conditions: Respiratory Failure; Mechanical Ventilation Complication; Newborn Morbidity; Bronchopulmonary Dysplasia

Treatments: Device: GE ventilator with two different modes

Study type: Observational

Funder types: Other

Identifiers

NCT04191239

2019512-2

Details and patient eligibility

About

Intubated preterm infants between 800-1200 grams and under 32 weeks of gestational age will start with PRVC ventilation mode, basal blood gases and work of breathing will measured. After that mode will shift to Bilevel Volume Guarantee mode for two hours than clinical and other parameters will be checked again. After this intervention, patients will allocated to PRVC or Bilevel VG group for remaining time.

Enrollment: 20 patients

Sex: All

Ages: 1 day to 3 months old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Need for mechanical ventilation
• 800-1200 grams of birthweight
• Surfactant received
• under 32 weeks of gestational age

Exclusion criteria

No need to intubation Congenital anomalies

Trial design

20 participants in 2 patient groups

PRVC

Description:

Preterm infants with need of mechanical ventilation will receive PRVC mode until extubation

Treatment:

Device: GE ventilator with two different modes

Bilevel VG

Description:

Preterm infants with need of mechanical ventilation will receive Bilevel VG mode until extubation

Treatment:

Device: GE ventilator with two different modes