Comparing Two Indirect Pulp Capping Agents for Permanent Teeth

Cairo University (CU)

Status: Not yet enrolling

Conditions: Deep Caries

Treatments: Drug: Silver diamine fluoride; Drug: Mineral trioxide aggregate

Study type: Interventional

Funder types: Other

Identifiers

NCT05425368

Indirect pulp capping

Details and patient eligibility

About

Aim of the study:

To evaluate clinical and radiographic success rates of silver diamine fluoride versus mineral trioxide aggregate as indirect pulp capping agents in deeply carious young first permanent molars.

Full description

Indirect pulp treatment has become a common maneuver in vital pulp therapy in recent years and is a procedure performed in teeth with deep carious lesions approximating the pulp but without any signs or symptoms of irreversible pulpal changes.

Silver Diamine Fluoride is used to arrest caries lesions in primary teeth but according to the AAPD,2021 more research is needed on the use of SDF to arrest caries lesions in permanent teeth.

Enrollment: 30 estimated patients

Sex: All

Ages: 9 to 14 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient and parent showing cooperation and compliance.
• Children 9-14 years old
• Vital deeply carious young first permanent molar(s) with complete root formation
• Asymptomatic teeth or without clinical symptoms of spontaneous pain
• Both genders will be included.

Exclusion criteria

• Children unable to return for recall visits.
• Any clinical signs of irreversible pulpitis or pulp necrosis (spontaneous pain, pain on percussion, abscess, sinus).
• Any radiographic sign of irreversible pulp pathologies or pulp necrosis (periapical radiolucency, internal or external root resorption)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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30 participants in 2 patient groups

silver diamine fluoride group

Experimental group

Description:

partial caries removal will be carried out then Silver Diamine Fluoride will be applied as indirect pulp capping agent and rubbed for 1 minute followed by Glass ionomer filling

Treatment:

Drug: Silver diamine fluoride

mineral trioxide aggregate group

Active Comparator group

Description:

partial caries removal will be carried out then mineral trioxide aggregate will be placed as indirect pulp capping agent followed by glass ionomer filling

Treatment:

Drug: Mineral trioxide aggregate