Comparison Between 2 Doses of Misoprostol Before Intrauterine Device

Assiut University

Status and phase: Completed; Phase 3; Phase 2

Conditions: Pain Relief

Treatments: Drug: misoprostol 200; Drug: misoprostol 400

Study type: Interventional

Funder types: Other

Identifiers

NCT02901561

MISO

Details and patient eligibility

About

The purpose of the investigators' study was to evaluate whether misoprostol will improve pain scores .

Full description

an intrauterine device can cause pain and discomfort in several ways: Use of the tenaculum to grasp the cervix and straighten the uterus for proper insertion; trans-cervical actions including measuring uterine depth, inserting the intrauterine device insertion tube, and removing the tube; and placement of the device in the uterus.

Enrollment: 212 patients

Sex: Female

Ages: 20 to 49 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• • Women not taken analgesics or anxiolytics in the 24 hours prior insertion

  • Women who will accept to participate in the study

Exclusion criteria

• Any contraindication to IUD placement

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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212 participants in 2 patient groups

misoprostol 200

Experimental group

Description:

misoprostol 200 microgram placed into the vagina 3 hours prior to having the intrauterine device inserted

Treatment:

Drug: misoprostol 200

misoprostol 400

Active Comparator group

Description:

misoprostol 400 microgram placed into the vagina 3 hours prior to having the intrauterine device inserted

Treatment:

Drug: misoprostol 400