Comparison Between Bupivacaine-Dexmedetomidine Versus Bupivacaine-Dexamethasone in Pericapsular Nerve Group (PENG) Block

Ain Shams University

Status and phase: Enrolling; Phase 1

Conditions: Hip Fractures; Post Operative Pain

Treatments: Drug: Pericapsular Nerve Group (PENG) Block

Study type: Interventional

Funder types: Other

Identifiers

NCT06294665

MD113/2023

Details and patient eligibility

About

The aim of this work is to compare the effectiveness of bupivacaine- dexmedetomidine mixture versus bupivacaine-dexamethasone mixture in PENG Block as Post-operative Analgesia in Hip surgeries

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Age 18-65 years.
2. Sex: Both sexes.
3. American Society of Anaesthesiologists (ASA) Physical Status Class I and II.
4. Scheduled for hip surgeries under spinal anaesthesia.

Exclusion criteria

1. Declining to give written informed consent.
2. History of allergy to the medications used in the study.
3. Contraindications to regional anesthesia (including patient refusal, coagulopathy and local infection).
4. Psychiatric disorder.
5. American Society of Anesthesiologists (ASA) Physical Status Class III and IV.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Group A : ( Bupivacaine + Dexmedetomidine )

Active Comparator group

Description:

Group A : will receive bupivacaine 0.25% + dexmedetomidine 1 mic/kg, total volume (20 ml)

Treatment:

Drug: Pericapsular Nerve Group (PENG) Block

Group B: ( Bupivacaine + Dexamethasone )

Active Comparator group

Description:

Group B : will receive bupivacaine 0.25% +dexamethasone (8 mg), total volume(20 ml).

Treatment:

Drug: Pericapsular Nerve Group (PENG) Block