Comparison Between Continuous and Pulse Itraconazole in Tinea Capitis in Children

Alexandria University

Status: Enrolling

Conditions: Tinea Capitis

Treatments: Drug: Itraconazole (ITZ)

Study type: Interventional

Funder types: Other

Identifiers

NCT07184203

0108853

Details and patient eligibility

About

A study to compare the efficacy of daily therapy versus pulse therapy of oral itraconazole in the treatment of tinea capitis in children based on clinical, mycological and dermoscopic evaluation.

Enrollment: 120 estimated patients

Sex: All

Ages: 5 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Tinea capitis patients with ages ranging from 5 to 18 year

Exclusion criteria

• Patients with contraindications to itraconazole
• Patients with associated scalp disease.
• Patients weighing less than 20 Kg.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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120 participants in 2 patient groups

Group A will receive itraconazole continuous daily regimen

Active Comparator group

Treatment:

Drug: Itraconazole (ITZ)

Group B will receive itraconazole pulse regimen

Active Comparator group

Treatment:

Drug: Itraconazole (ITZ)