Comparison Between Different Psychotherapy Interventions Regarding Their Effect on Substance Craving

Sara Harby

Status: Completed

Conditions: Addiction Opiate

Treatments: Behavioral: cognitive behavioral therapy,mindfulness based relapse prevention,twelve-step therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT05256485

RPC£0521190906

Details and patient eligibility

About

the study aim is to compare betwenn the effect of mindfulness based relapse prevention and other evidence based psychotherapy interventions regaring substance craving.

Full description

In this prospective study, the population included opioid-dependent men (aged 18-50 years), some of them were admitted to El Maamora hospital and others were attendees in NA. To conduct this research, considering the drop-out rate, the list of 60 persons applying for treatment was prepared based on inclusion and exclusion criteria.

Then, three groups of 20 were randomly selected and placed in three intervention groups, group one received CBT, group two received MBRP, and group three received twelve-step therapy.

The subjects were assigned randomly to the treatment condition via a computer-generated random number with the aid of trained staff at the clinic blindly.

All participants completed the measurement scales immediately after detoxification (pre-test) and after the end of therapeutic sessions (post-test).

Enrollment: 45 patients

Sex: Male

Ages: 15 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age: 15-50 years.
• Male gender.
• Patients meet DSM-5(3) criteria of opioid abuse.
• Had completed detoxification in a treatment center.
• Willing to give consent they will be randomly assigned to either CBT, MBRP, or twelve-step treatment group.
• Patients have dual diagnoses.
• Patients have poly-substance use disorder.

Exclusion criteria

• Participants with significant cognitive disorder.
• Participants with suicidal thoughts.
• Participants with any organic condition affecting stress response and so craving such as hypertension, respiratory or cardiovascular disorders.
• Participants taking any medications (e.g., antipsychotics in high doses) known to affect the stress response.
• Participants relapsed to drug abuse during therapy.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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45 participants in 3 patient groups

cognitive behavioral therapy

Active Comparator group

Description:

Standard CBT comprises an array of approaches directed toward modifying dysfunctional thinking and behavior. The two critical components are analysis of thoughts, feelings, and behaviors, as well as skills training for achieving active behavior and thought modification.

Treatment:

Behavioral: cognitive behavioral therapy,mindfulness based relapse prevention,twelve-step therapy

mindfulness based relapse prevention

Active Comparator group

Description:

MBRP training is based on a two-component process: 1. Attention to present moment experience, even if it includes craving or negative emotion. 2. An accepting attitude towards this experience letting it be exactly as it is, without judging it or reacting to it.

Treatment:

Behavioral: cognitive behavioral therapy,mindfulness based relapse prevention,twelve-step therapy

twelve-step therapy

Active Comparator group

Description:

12-step therapy was based on strengthening conscious contact with God and awakening spirituality through prayer and meditation

Treatment:

Behavioral: cognitive behavioral therapy,mindfulness based relapse prevention,twelve-step therapy