Comparison Between Local and Imported Skin Prick Testing Result of Rat and Mouse Allergen Extracts

Mahidol University

Status

Completed

Conditions

Allergic Rhinitis Due to Animal Hair and Dander

Treatments

Diagnostic Test: rat and mouse skin test

Study type

Interventional

Funder types

Other

Identifiers

NCT03645161

789/2560 (EC 2)

Details and patient eligibility

About

In respiratory allergy patients, skin prick test results of local rat and mouse allergen extracts are not significant different from imported ones

Full description

Many researches proposed that rodent deteriorate symptoms in patients with respiratory allergy who sensitized. The test that can identify rodent sensitization will be very useful. The investigators found lots of problems from imported mouse and rat allergen extract, eg. expensive cost and hard to find importing agency in Thailand. Making own local allergen extract will be the good solution for the country. This study aim to compare the results of locally rat and mouse allergen to imported ones.

Enrollment

230 patients

Sex

All

Ages

3 to 60 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients age 3 to 60 years old who diagnosed with asthma or allergic rhinitis
Patient must not take these following medication at least 7 days before doing the skin prick test: antihistamine, oral corticosteroid (more than 20 mg/day of prednisolone), topical steroid that was apply on skin test area.

Exclusion criteria

Pateints who have other chronic underlying disease e.g. obesity, heart disease and liver disease
Patient with allergic asthma who is still uncontrollable.
Patient with active severe atopic dermatitis
Patient who are pregnant or in lactating period
Patient or parent deny to join in the study