Comparison Between Metallic Clip Ligation and Suture Ligation of Appendicular Stump in Laparoscopic Appendectomy

Jinnah Hospital

Status: Not yet enrolling

Conditions: Laparoscopic Appendectomy

Treatments: Device: Suture ligation of appendicular stump; Device: Metallic clip ligation of the appendicular stump

Study type: Interventional

Funder types: Other

Identifiers

NCT07129746

Jinnah Hospital Lahore

Details and patient eligibility

About

Laparoscopic appendectomy is the standard procedure for acute appendicitis. Among the various steps of the procedure one of the rate limiting step is the ligation of the appendicular stump which can be done using suture material, metallic clips and hem o loks. This study compares the effect the using metallic clips versus suture material in the ligation of appendicular stump in terms of length of surgery and associated intra-operative complications. The patients included will be within the age group of 15-60 years, with BMI of 18-28kg/m2, and with acute appendicitis of upto grade 3. The data will be analyzed using SPSS a p value of <0.05 will be considered as statistically significant.

Enrollment: 10 estimated patients

Sex: All

Ages: 15 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Both genders, within the age bracket of 15 years - 60 years.
2. With a BMI within the range of 18 - 28 kg/m2.
3. With a diagnosis made by a consultant surgeon and the grade of appendicitis upto 3.

Exclusion criteria

1. Patients with long standing comorbidities including chronic liver disease, diabetes mellitus, chronic kidney disease and hemorrhagic disorders.
2. Patients taking anticoagulants, carrier of active cases of Hepatitis B, C and/or HIV.
3. Patients on immunosuppression therapy. Diameter of appendicular stump of more than 10mm, perforated appendix, laparoscopic appendectomy converted to open appendectomy pelvic appendicitis and sub-hepatic appendicitis.

Trial design

Primary purpose: Device Feasibility

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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10 participants in 2 patient groups

Group A - Patients undergoing metallic clip ligation

Active Comparator group

Description:

One of the standard methods of appendicular stump ligation

Treatment:

Device: Metallic clip ligation of the appendicular stump

Group B - Patients undergoing suture material ligation of appendicular stump

Experimental group

Description:

A feasible testing method with an anticipated increase in the length of surgery

Treatment:

Device: Suture ligation of appendicular stump