Comparison Between Perineural and Systemic Effect of Dexamethasone for Interscalene Brachial Plexus Block.

Hillel Yaffe Medical Center

Status: Unknown

Conditions: Analgesia

Treatments: Drug: Bupivacaine; Drug: Dexamethasone

Study type: Interventional

Funder types: Other

Identifiers

NCT02190760

HYMC-13.7.14

Details and patient eligibility

About

The addition of dexamethasone (DxaM) to local anesthetic may significantly prolong the duration of a block. The aim of this study is to determine whether this a systemic or local effect.

Enrollment: 90 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pre-surgical patients for arthroscopic or open shoulder surgery

Exclusion criteria

• Skin infection near block site
• Allergy to local anesthetics
• Peripheral neuropathy
• Proven opioid dependency
• Coagulopathy
• Dementia

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Single Blind

---

90 participants in 3 patient groups

Group I (ISB-P)

Active Comparator group

Description:

Interscalene block with perineural injection of dexamethasone 0.1 mg/kg

Treatment:

Drug: Dexamethasone

Drug: Bupivacaine

Group II (ISB-S)

Active Comparator group

Description:

Interscalene block with systemically injection of dexamethasone 0.1 mg/kg.

Treatment:

Drug: Dexamethasone

Drug: Bupivacaine

Group III - ISB-C

Active Comparator group

Description:

Interscalene block without adjuvant.

Treatment:

Drug: Bupivacaine