Comparison Between Propofol-remifentanil Total Intravenous Anesthesia and Desflurane-remifentanil Balanced Anesthesia With Regard to Post-anesthetic Functional Recovery Measured With QoR-40 in Vitrectomy

Yonsei University

Status: Completed

Conditions: Vitrectomy Operation Under General Anesthesia

Treatments: Drug: desflurane and remifentanil; Drug: fresofol and remifentanil

Study type: Interventional

Funder types: Other

Identifiers

NCT02212340

3-2014-0104

Details and patient eligibility

About

Total intravenous anesthesia (TIVA) and inhalation anesthesia are both widely and safely used, and there are many clinical trials comparing these on various aspects of anesthesia. However, there have not been studies comparing the quality of recovery from the different methods of general anesthesia in vitrectomy. In this study, the investigators compare the functional recovery after general anesthesia in TIVA and inhalation anesthesia with QoR-40 questionnaire in vitrectomy.

Enrollment: 84 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients (20-80 years old) scheduled for vitrectomy surgery undergoing general anesthesia.
2. ASA 1-3

Exclusion criteria

1. Patients with allergy to anesthetic agents
2. Anticipated difficult airway
3. BMI > 30 kg/m2
4. Chronic obstructive pulmonary disease
5. Heart failure 6. Unstable angina

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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84 participants in 2 patient groups

TIVA group

Experimental group

Description:

Anesthesia is maintained with fresofol and remifentanil

Treatment:

Drug: fresofol and remifentanil

Des group

Active Comparator group

Description:

Anesthesia is maintained with desflurane and remifentanil

Treatment:

Drug: desflurane and remifentanil