Comparison Between Transcranial Stimulation Protocols With Continuous Current in the Chronic Migraine (NEUROMIG)

Federal University of Paraíba

Status: Completed

Conditions: Chronic Migraine

Treatments: Other: tDCS

Study type: Interventional

Funder types: Other

Identifiers

NCT03414203

NEUROMIG

Details and patient eligibility

About

This study aims to compare the effects of transcranial direct current stimulation on the clinical and cognitive function in patients with chronic migraine.

Full description

The patients will be randomized into 1 of 3 groups: active tDCS for 15 minutes, active tDCS for 15 minutes, with an interval of 20 minutes and more 15 minutes os stimulation, sham tDCS for 15 minutes. The tDCS will be applied for 10 days over 2 weeks.

Enrollment: 31 patients

Sex: Female

Ages: 20 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• females
• clinical diagnosis of chronic migraine according to the International Classification of Headaches Disorders (ICHD-3 beta).

Exclusion criteria

• headache attributable to some pathological condition, associated neurologic or neuropsychiatric disease
• use of central nervous system modulating drugs
• pregnancy
• metallic head implants
• use of a cardiac pacemaker

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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31 participants in 3 patient groups

active tDCS

Active Comparator group

Description:

Active tDCS for 15 minutes for 10 days over 2 weeks. Intensity: 2 milliampere. Placement: anode - left DLPFC; cathode - right supraorbital region

Treatment:

Other: tDCS

active tDCS with interval

Experimental group

Description:

Active tDCS for 15 minutes, interval of 20 minutes and more 15 minutes for 10 days over 2 weeks. Intensity: 2 milliampere. Placement: anode - left DLPFC; cathode - right supraorbital region

Treatment:

Other: tDCS

sham tDCS

Sham Comparator group

Description:

Sham tDCS for 15 minutes for 10 days over 2 weeks. The stimulation is non-active. Placement: anode - left DLPFC; cathode - right supraorbital region

Treatment:

Other: tDCS