Comparison Between Turquoise and Blue Light in Treatment of Neonatal Jaundice Using Light Emission Diodes

University of Aarhus

Status: Completed

Conditions: Uncomplicated Neonatal Hyperbilirubinemia

Treatments: Other: Phototherapy

Study type: Interventional

Funder types: Other

Identifiers

NCT02154165

PKV 2013

Details and patient eligibility

About

The optimal wavelength for phototherapy for neonatal jaundice remains to be clarified by clinical studies. Previous iv vivo studies have shown that turquoise light at wavelength about 490 nm is more efficacious than blue light at wavelength 460 nm, which is the golden standard in phototherapy treatment today. Though, previous studies used light tubes, today we use light emitting diodes (LED'S).

The overall aim of this study was therefore to compare the efficacy of turquoise LED's versus blue LED's for decreasing total serum bilirubin in neonates with gestational age > 33 weeks and uncomplicated hyperbilirubinemia.

Enrollment: 90 patients

Sex: All

Ages: 33+ weeks old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Newborns with gestational age >33 weeks and neonatal hyperbilirubinemia requiring treatment with phototherapy according to the national guidelines

Exclusion criteria

• Haemolytic disease (Rhesus and Kell blood type isoimmunization, spherocytosis)
• Liver disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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90 participants in 2 patient groups

Blue light wavelenght 460 nm

Active Comparator group

Treatment:

Other: Phototherapy

Turquoise light wavelength 499 nm

Active Comparator group

Treatment:

Other: Phototherapy