Comparison Efficacy in Patients With Asthma Using Foster MDI and Relvar Medications

Far Eastern Memorial Hospital

Status and phase: Unknown; Phase 4

Conditions: Asthma

Treatments: Drug: Foster

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT04185129

Foster 001

Details and patient eligibility

About

This is a randomized study to compare asthma patients using Foster or Relvar.

Full description

The Global Asthma Association (GAA) and the World Allergy Organization (WAO) recently issued statements stating that the small airway is caused by asthma and chronic obstructive pulmonary disease (COPD). Both pathogenesis and treatment play an important role. The small airway is an airway with diameter less than 2 mm and is one of the main sites where airflow obstruction occurs. Small particles (<2 μm) and large particles are more likely to deposit in the distal airways, and have shown to have better effects on asthma and pulmonary obstruction. At the same time, real-life research has also shown that extra-fine particles provide better asthma control than large particles, and can better improve quality of life.The aim of the study is to compare the efficacy of asthma inhalers between extra-fine particles and non-extra-fine particles.

Enrollment: 200 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients diagnosis with asthma with treatment naive
• asthma patients with poor controlled status

Exclusion criteria

• COPD
• smoking history
• pregnancy
• cardiaovascular disease
• patients with acute respiratory infection

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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200 participants in 2 patient groups

Foster

Experimental group

Description:

uncontrolled asthma patients were randomized into Foster treatment group

Treatment:

Drug: Foster

Relvar

Active Comparator group

Description:

uncontrolled asthma patients were randomized into Relvar treatment group

Treatment:

Drug: Foster