Oral Fluid vs IV Fluid After Primary TKA

Thammasat University Hospital

Status: Enrolling

Conditions: Oral Fluid Replacement; Total Knee Arthroplasty; Osteoarthritis, Knee

Treatments: Dietary Supplement: IV fluid; Dietary Supplement: Oral fluid

Study type: Interventional

Funder types: Other

Identifiers

NCT06288815

TUH oral fluid TKA

Details and patient eligibility

About

The goal of this study is to compared efficacy of oral fluid and intravenous fluid after primary unilateral total knee arthroplasty.

The main question it aims to answer is:

Does oral fluid replacement after primary unilateral total knee arthroplasty provide a patient recover faster than intravenous fluids replacement?

Enrollment: 130 estimated patients

Sex: All

Ages: 40 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 40-85 years old
• ASA I, II
• Primary osteoarthritis

Exclusion criteria

• Diuretics use
• Morbid obesity
• Previous knee surgery
• Cannot undergo spinal anesthesia

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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130 participants in 2 patient groups

Oral fluid

Experimental group

Description:

* NPO (8hr for food, 2hr for water) * Intraoperative IV fluid at least 1 liter * Post operative (Off IV fluid, allow oral fluid as protocol at least 24hr)

Treatment:

Dietary Supplement: Oral fluid

IV fluid

Active Comparator group

Description:

* NPO (8hr for food, 2hr for water) * Intraoperative IV fluid at least 1 liter * Post operative (IV fluid as protocol at least 24hr, allow oral fluid as usual)

Treatment:

Dietary Supplement: IV fluid