Comparison of 1 vs 3 Sets of Resistance Training on Muscular Hypertrophy

Kansas Board of Regents

Status: Completed

Conditions: Obesity

Treatments: Other: Amount of resistance offered in training

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT01107691

HSCL17623

NIDDKRO180832 (Other Grant/Funding Number)

Details and patient eligibility

About

This study is designed to investigate the effects of two levels of resistance weight training on body composition, energy expenditure, and energy intake in men and women. The weight training will take about one hour to complete. Participants will perform the training 3 days per week for 9 months in a private exercise room equipped with state of the art equipment and a personal trainer to help guide you through the exercises.

The project lasts 21 months total with one follow-up visit 1-year from your last training date. You will be required to stay in the Lawrence area and train 3 day/week over the summer & holidays.

Full description

We propose to conduct a randomized controlled efficacy trial (RT-1 set vs. RT-3 sets vs. non exercise control) to evaluate the potential for a longer intervention (9 months RT with body composition assessments 1 yr post RT completion) with a higher volume of RT (3 sets) to enhance the effects on body composition and energy expenditure observed in the pilot, and to determine the impact of the 2 levels of RT on free-living energy balance (expenditure by doubly labeled water and intake by digital photography and 24-hr recalls). This investigation will be conducted in a sample of healthy, normal and overweight, sedentary, young adult men and women; a group at high risk for development of overweight and obesity. The specific aims of this project are to determine the impact of the volume (1 vs. 3 sets) of a progressive RT protocol for inducing muscular hypertrophy, as recommended by the American College of Sports Medicine, on body weight and body composition (fat mass, fat-free mass (FFM), % body fat) and energy balance. Our results will provide information relative to the minimum volume of RT that may be associated with body weight/fat gain which may inform the development of guidelines for RT to prevent weight gain or to alter body composition. If RT has a favorable impact on energy balance and body composition, it may provide an attractive alternative to aerobic exercise for weight management for busy young adults, as RT requires minimal time, and no need to change clothes or shower (i.e. minimal or no sweating).

Enrollment: 169 patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI 22-<30
• 18- 30 years old
• sedentary
• no medications
• weight stable for at least 3 months

Exclusion criteria

• Tobacco/Drug user
• metabolism altering medication
• gain/lost 10lbs in the last 3 months
• current exerciser

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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169 participants in 3 patient groups

Resistance training

Experimental group

Description:

1 set of progressive resistance training per session

Treatment:

Other: Amount of resistance offered in training

3 sets per session

Experimental group

Description:

3 sets of progressive resistance training per session

Treatment:

Other: Amount of resistance offered in training

Control

No Intervention group

Description:

Non exercise control group