Comparison of 18-F Sodium Fluoride Uptake in Culprit Plaques Between Acute Coronary Syndrome and Stable Angina

CHEOL WHAN LEE, MD, PhD.

Status: Terminated

Conditions: Coronary Artery Diseases

Treatments: Other: 18-F Sodium Fluoride Uptake in Positron emission tomography

Study type: Interventional

Funder types: Other

Identifiers

NCT01665248

AMCCV2012-03

Details and patient eligibility

About

The purpose of this study is to evaluate the correlations between active calcification and vulnerable plaque.

Enrollment: 20 patients

Sex: All

Ages: 21+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age more than 20
• Acute coronary syndrome or stable angina

Exclusion criteria

• Contraindications to the use of heparin, aspirin, clopidogrel, stainless metal, contrast media
• Acute ST segment elevation myocardial infarction within 12hours, heart failure, cardiac shock
• Any serious medical comorbidity such that the subject's life expectancy is less than 24 months
• Ejection fraction less than 30
• Serum creatinine level of 1.5mg/dl and over
• Vasculitis
• Unwillingness or inability to cooperate or to give informed consent

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

stable angina pectoris or acute coronary syndrome

Other group

Treatment:

Other: 18-F Sodium Fluoride Uptake in Positron emission tomography