Comparison of 2 Ventilatory Support Strategies During Coronavirus Disease 2019 (Covid-19) Pneumonia (STRATIC)

Intermunicipal Hospital Center Toulon

Status: Completed

Conditions: COVID-19

Treatments: Procedure: Non-invasive ventilation strategies; Procedure: Invasive ventilation strategy

Study type: Observational

Funder types: Other

Identifiers

NCT04799691

2021-CHITS-004

Details and patient eligibility

About

This retrospective monocentric study compares 2 ventilatory support strategies on outcomes (length of stay, intubation, mortality) in patients admitted in Intensive Care Unit with Covid-19 related pneumonia : invasive strategy used during the first period and non-invasive strategies (Continuous Positive Airway Pressure, High Flow Nasal Canula, Prone Position) used during the second period.

Enrollment: 133 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient with confirmed SARS COV2 infection
• Acute Respiratory Distress Syndrome
• Patient more than 18 year old

Exclusion criteria

• Intensive Care Unit admission for extra pulmonary failure
• "Do Not Reanimated" order
• Patient from another Intensive Care Unit
• Patient objection
• Judicial protection

Trial design

133 participants in 2 patient groups

Invasive strategy group

Description:

Patients admitted in ICU with Covid-19 related pneumonia during COVID19 first period.

Treatment:

Procedure: Invasive ventilation strategy

Non-invasive strategy group

Description:

Patients admitted in ICU with Covid-19 related pneumonia during COVID19 second period.

Treatment:

Procedure: Non-invasive ventilation strategies