Comparison of 6-fluoro-[18F]-L-dihydroxyphenylalanine (18F-DOPA) Positron Emission Tomography (PET) and Multiparametric Resonance Magnetic Imagery (RMI) in Initial Exploration of Glial Tumors (GLIROPA)

Center Eugene Marquis

Status: Completed

Conditions: Brain Neoplasms; Adult Brain Tumor

Treatments: Diagnostic Test: PET imagery

Study type: Interventional

Funder types: Other

Identifiers

NCT03525080

2017-4-52-010

Details and patient eligibility

About

For patient having a brain tumor, RMI is the standard exam for tumor characterization and determines initial surgery.

The aim of this study is to assess if PET could provide additional information that could have an impact on surgery (indication and planification)

Enrollment: 16 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Suspected glial resectable tumor
• Free and informed consent
• Affiliated to French social security

Exclusion criteria

• Suspected high grade glioma
• Surgical emergency
• Pregnant or breastfeeding woman
• Patient deprived of their liberty or under guardianship
• Patient not able to follow study medical monitoring for geographical, social or psychological reasons
• Treated with carbidopa, catechol-O-methyl transferase inhibitor, haloperidol, reserpine within 2 weeks before PET imagery

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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16 participants in 1 patient group

PET Arm

Experimental group

Treatment:

Diagnostic Test: PET imagery