Comparison of a Face Cream Plus a Laser Procedure and Face Cream Alone in Treatment of Excessive Face Hairs in Female

Khyber Teaching Hospital

Status and phase: Enrolling; Phase 4

Conditions: Hirsuitism

Treatments: Drug: Eflornithine Topical; Radiation: Instense pulsed light

Study type: Interventional

Funder types: Other

Identifiers

NCT06976424

59/DME/KMC

Details and patient eligibility

About

The study compares the effects of a cream alone and a combined effect of cream and laser for the treatment of excessive facial hairs in women .

Full description

Hirsuitism refers to excessive terminal hairs in females, following a distribution pattern typically associated with male. It is associated with either increase response of hair follicles to androgen or either increase level of circulating androgens.The treatment options available are topical creams like eflornithine and laser treatments for hair removal. This study aims to conduct the comparison of a eflornithine cream and intense pulsed light laser versus eflornithine cream alone for the treatment of excessive facial hairs.

Enrollment: 122 estimated patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Gender (Female) Age between 18-45 Years Women with hirsutism as mentioned in the operational definition

Exclusion criteria

Pregnant women Women with severe acne Women with immunodeficiency

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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122 participants in 2 patient groups

GroupA

Experimental group

Description:

This group is treated with combination of eflornithine cream and intense pulsed light for a period of three month.

Treatment:

Radiation: Instense pulsed light

Drug: Eflornithine Topical

Drug: Eflornithine Topical

Group B

Experimental group

Description:

This group is treated with eflornithine cream twice daily only for a period of three month

Treatment:

Drug: Eflornithine Topical

Drug: Eflornithine Topical