Comparison of Analgesic Efficacy of US Guided ESP Block With Port Site Infiltration Following Laparoscopic Cholecystectomy

Assiut University

Status: Completed

Conditions: Postoperative Pain

Treatments: Procedure: Port site infiltration; Drug: Lidocaine 2%; Procedure: Erector spinae plane block; Device: Ultrasound machine (Mindray DP 9900 plus; Mindray Bio-Medical Electronics, Shenzhen, China); Drug: Bupivacaine 0.5%

Study type: Interventional

Funder types: Other

Identifiers

NCT04167176

ABC-3-DE

Details and patient eligibility

About

To compare the efficacy of ultrasonography (USG)-guided bilateral Erector spinae plane block (ESPB) with port-site infiltration using bupivacaine for post-operative analgesia after laparoscopic cholecystectomy with a hypothesis that both Erector spinae plane block and port-site infiltration are effective in providing post-operative analgesia.

Enrollment: 44 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with the American Society of Anesthesiologists (ASA) physical status I/II,
• Age between 18 and 60 years with a body mass index (BMI) of 18-35 kg/m2,
• Patients scheduled for elective laparoscopic cholecystectomy.

Exclusion criteria

• Allergy to local anaesthetics,

• Infection at the site of injection,

  •, Coagulopathy,

• Chronic pain syndromes,

• Prolonged opioid medication,

• Patients who received any analgesic 24 h before surgery

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

44 participants in 2 patient groups

Erector spinae plane block

Active Comparator group

Description:

ultrasound guided ESP Block after anaesthesia induction

Treatment:

Drug: Bupivacaine 0.5%

Device: Ultrasound machine (Mindray DP 9900 plus; Mindray Bio-Medical Electronics, Shenzhen, China)

Drug: Lidocaine 2%

Procedure: Erector spinae plane block

Port site infiltration technique

Active Comparator group

Description:

After the induction of anaesthesia, pre-incisional port-site infiltration will be performed by the same surgeon every time with 20 ml of Local anesthetic (LA) mixture that will be divided equally between port sites

Treatment:

Drug: Bupivacaine 0.5%

Procedure: Port site infiltration

Drug: Lidocaine 2%