Comparison of Analgesic Efficiency Between Serratus Block and Paravertebral Block in Video-assisted Thoracic Surgery. Double-blind Randomized Comparative Non-inferiority Study (BSBP)

Centre Hospitalier Universitaire de Nice

Status: Completed

Conditions: Anesthesia

Treatments: Procedure: Serratus anesthesia technique; Procedure: Paravertebral anesthesia technique

Study type: Interventional

Funder types: Other

Identifiers

NCT04983836

19-AOI-04

Details and patient eligibility

About

Currently, the 2 main techniques of regional loco anesthesia in perioperative analgesic management of the thoracotomy remains the establishment of a thoracic epidural or paravertebral block. On the other hand, there is no standard of perioperative analgesic management in the case of thoracic surgery under video-thoracoscopy. The video-thoracoscopy, by its mini-invasive character, makes the levels of pain lower in post-operative questioning the benefit/risk balance of the paravertebral block. In 2013, Blanco published a new technique of locoregional anesthesia called the block Serratus allowing analgesia of a homolateral thorax hemi The latter by its simplicity of realization and its lesser risk is growing in thoracic surgery. This pilot study finds an equivalence in total oxycodone consumption in the first 2 post-operative days with a number of complications related to the serratus block lower than the serratus block compared to the paravertebral block in preoperative surgery.

Enrollment: 150 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 18 years
• Patient who has given their free, informed and signed consent
• Social security affiliation;

Exclusion criteria

• pregnant woman
• guardianship / curatorship / private patient under public law
• surgery to be performed urgently (less than 24 hours)
• surgery redux
• thoracotomy surgery
• sternotomy surgery
• pleurectomy
• patient participating simultaneously in another research that may interfere with results of the study
• severe abnormality of haemostasis (80,000/ml platelets) and/or coagulation (TP 50%, factor V 50%).
• Prior use of morphine;
• chronic pain/chest neuropathies
• sepsis
• patients with insulin-dependent diabetes and/or diabetic neuropathy.
• severe kidney or liver failure.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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150 participants in 2 patient groups

Serratus Block

Experimental group

Treatment:

Procedure: Serratus anesthesia technique

Paravertebral Block

Other group

Treatment:

Procedure: Paravertebral anesthesia technique