Comparison of Antimicrobial Coated Ureteral Stents With Non-coated Stents

Mansoura University

Status and phase: Completed; Phase 4

Conditions: Quality of Life

Treatments: Device: Antimicrobeal coated stents

Study type: Interventional

Funder types: Other

Identifiers

NCT02266368

Antimicrobeal ureteral stents

Details and patient eligibility

About

This study will be conducted to compare the efficacy of antimicrobial coated ureteral stent with non-coated stents in prevention of UTI in patients with ureteral stents

Full description

The efficacy of antimicrobial coated of ureteral stent with silver sulphadiazine in prevention of UTI in patients with ureteral stents will be studied by comparining the results of urine and stent cultures with patients who had non-coated ureteral stents. The impact of antimicrobeal stent coating on patients' quality of life will be evaluated with comparing the scores of ureteral stent symptom questionnaire between both groups.

Enrollment: 110 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who will undergo ureteral stent placement

Exclusion criteria

• Patients allergic to sulpha containing medications
• Ureteral stent insertion for infected hydronephrosis
• Patients who developed septic complications requiring antibiotic treatment after stent placement
• Patients who need bilateral stents
• Patients with chronic kidney disease grade IV and V (GFR <30ml/min)
• Immunocompromised patients as those with malignancy or organ transplantation.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

110 participants in 2 patient groups

Control group

No Intervention group

Description:

This arm will include patients with non-coated stents

Antimicrobeal group

Active Comparator group

Description:

This arm will include patients with antimicrobeal coated stents

Treatment:

Device: Antimicrobeal coated stents