Comparison of AOCT and AOPT for the Treatment of Medial Large Cystic OLT

Peking University

Status

Completed

Conditions

Osteochondral Lesions of the Talus

Treatments

Procedure: AOPT

Procedure: AOCT

Study type

Observational

Funder types

Other

Identifiers

NCT04950335

M2021055

Details and patient eligibility

About

Autologous osteoperiosteal transplantation using tissue harvested from the iliac crest is used to treat large cystic osteochondral lesions of the talus. This study is to compare clinical and radiological outcomes between patients undergoing AOPT and those undergoing AOCT for large cystic OLTs.

Full description

From March 2015 to March 2018, 23 patients who underwent AOPT and 23 patients who underwent AOCT to treat large cystic OLTs (>10mm) were retrospectively evaluated. For comparability, the two groups were matched based on their demographics, including sex, age, body mass index, side of injury, follow-up period, and the preoperative cyst volume. Clinical outcomes were assessed using the visual analog scale (VAS), the American Orthopaedic Foot & Ankle Society (AOFAS) score, and the Tegner score. Donor-site morbidity was recorded according to the symptoms, including pain, stiffness, swelling and discomfort. Radiological outcomes were evaluated using the Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score, and the International Cartilage Repair Society (ICRS) score was obtained during second-look surgery.

Enrollment

46 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

presence of medial large cystic OLTs (>10 mm in diameter) confirmed by preoperative magnetic resonance imaging (MRI)
patients who underwent either primary AOPT or AOCT

Exclusion criteria