Comparison of Aqueous and Plasma Glucose Level in Diabetic Patients

Sheba Medical Center

Status: Unknown

Conditions: Diabetes Mellitus

Treatments: Other: Glucose measurement

Study type: Interventional

Funder types: Other

Identifiers

NCT02750098

296416

Details and patient eligibility

About

Comparison of aqueous and plasma glucose level in diabetic patients

High glucose concentrations in aqueous humor are thought to be related of diabetic ocular injury, including cataract and diabetic keratopathy. The primary mechanisms are nonenzymatic glycation, oxidative stress and activation of polyol pathway. However, glucose concentrations in aqueous humor of diabetic patients was only examined in a few patients in the past.

This study will compare glucose concentration in blood plasma and aqueous humor in diabetic patients undergoing cataract surgery. Perioperative Hemoglobin A1c concentrations will also be examined. Correlation between these parameters will be analyzed.

Enrollment: 25 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diabetic patients planed for elective cataract surgery

Exclusion criteria

• s/p traumatic eye injury
• past or current uveitis
• patients using prescription eye drops except lubricants

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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25 participants in 1 patient group

Diabetic patients

Experimental group

Description:

Diabetic patients planned to undergo elective cataract surgery

Treatment:

Other: Glucose measurement