Comparison of ARDS COVID-19 (WHO) vs ARDS Influenza in the ICU

Central Hospital, Nancy, France

Status: Completed

Conditions: Influenza; COVID-19 Acute Respiratory Distress Syndrome; ARDS

Treatments: Other: no intervention

Study type: Observational

Funder types: Other

Identifiers

NCT04941092

2021PI076

Details and patient eligibility

About

Since the beginning of the SARS CoV 2 pandemia, the SARS CoV 2 was frequently compared with the seasonal influenza virus. However, few studies compared patients presenting acute respiratory distress syndrome (ARDS) induced by these viruses, with results being discordant. Our study means to compare mortality and morbidity of patients hospitalized in an intensive care unit (ICU) with ARDS induced by SARS CoV-2 and seasonal influenza.

Enrollment: 157 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients hospitalized in ICU
• under mechanical ventilation
• presenting an ARDS according to the Berlin definition
• induced by either influenza or SARS CoV 2

Exclusion criteria

• pregnant women
• mechanical ventilation>48 hours before admission

Trial design

157 participants in 2 patient groups

patients with ARDS induced by SARS CoV 2

Treatment:

Other: no intervention

patients with ARDS induced by influenza

Treatment:

Other: no intervention