Comparison of Articaine and Prilocaine for Extraction of Maxillary Teeth

T

Taibah University

Status and phase

Completed
Phase 4

Conditions

Dental Extraction
Maxillary Teeth
Overcoming the Failure of Anaesthesia

Treatments

Drug: Prilocain 3%
Drug: Adrenalin
Drug: Felypressin
Drug: Articaine 4%

Study type

Interventional

Funder types

Other

Identifiers

NCT04236115
Taibah dental College

Details and patient eligibility

About

Ninety-five patients, aged between 16 and 70 years old, were included in this study. Patients were divided into two groups. Group one received Articaine 4% with 1:00.000 Adrenalines. Group two received Prilocaine with 3% Felypressin (0.03 I.U. per ml). Onset time of anaesthesia was objectively evaluated by using electronic pulp testing.

Full description

85 patients in this study had successful local anaesthetic followed by extraction within the study duration time (10 minutes). However, there were six patients with failure anaesthesia (5 in prilocaine group and 1 in articaine group). By application Person's Chi-square test (x2), there were no significant differences in the number of the episodes of the anaesthetic success between articaine and prilocaine groups at time intervals (P-value = 0.5). T- test showed there have been no important variations within the mean onset time of anaesthesia for articaine and prilocaine buccal infiltrations (P-value =0.1).

Enrollment

95 patients

Sex

All

Ages

16 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients have one or two upper teeth for extraction, subject tooth or its adjacent must be vital, healthy patient or patient with mild systemic diseases (class I or II according to American Society of Anesthesiology).

Exclusion criteria

Patients excluded from this study if they have allergy to local anaesthetic agents or need surgical, or multiple teeth extraction.

Trial design

95 participants in 2 patient groups

Articaine 4% with 1:00.000 Adrenaline
Active Comparator group
Description:
if the patient was in articaine group, buccal infiltration technique was applied by inserting a short needle at the height of buccal sulcus along the long axis of the subject tooth for extraction.
Treatment:
Drug: Articaine 4%
Drug: Adrenalin
Prilocaine with 3% Felypressin (0.03 I.U. per ml)
Active Comparator group
Description:
if the patient was in prelocaine group, buccal infiltration technique was applied by inserting a short needle at the height of buccal sulcus along the long axis of the subject tooth for extraction.
Treatment:
Drug: Felypressin
Drug: Prilocain 3%

Trial contacts and locations

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Data sourced from clinicaltrials.gov

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