Comparison of Balance, Activity-specific Balance Confidence and Quality of Life in Parkinson's Patients

Nigde Omer Halisdemir University

Status: Completed

Conditions: Idiopathic Parkinson's Disease

Treatments: Diagnostic Test: Assessment

Study type: Observational

Funder types: Other

Identifiers

NCT05671341

2022/106

Details and patient eligibility

About

Parkinson's disease is characterized by cardinal motor signs and motor freezing, gait, posture and balance disorder. About 80% of the causes of falls in Parkinson's patients are due to postural instability and motor freezing, and patients' quality of life is significantly affected. Loss of balance and falls, which are frequently experienced in Parkinson's patients, cause individuals to feel insecure during activities. It is thought that the quality of life of PD patients whose movements are restricted due to the fear of falling may also be negatively affected. The neutrophil/lymphocyte ratio is a marker of peripheral inflammation. The relationship of peripheral inflammation to balance, activity-specific balance confidence, and quality of life in individuals is unclear. The aim of this study was to compare balance, activity-specific balance confidence, quality of life, and the relationship between neutrophil/lymphocyte ratio in Parkinson's patients with and without freezing.

Full description

Parkinson's disease is characterized by cardinal motor signs and motor freezing, gait, posture and balance disorder. About 80% of the causes of falls in Parkinson's patients are due to postural instability and motor freezing, and patients' quality of life is significantly affected. Loss of balance and falls, which are frequently experienced in Parkinson's patients, cause individuals to feel insecure during activities. It is thought that the quality of life of PD patients whose movements are restricted due to the fear of falling may also be negatively affected. The neutrophil/lymphocyte ratio is a marker of peripheral inflammation. The relationship of peripheral inflammation to balance, activity-specific balance confidence, and quality of life in individuals is unclear.

The aim of this study was to compare balance, activity-specific balance confidence, quality of life, and the relationship between neutrophil/lymphocyte ratio in Parkinson's patients with and without freezing.

A total of 20 Parkinson's Disease age of older the 50 participate in the research. Participants were divide into two groups with and without freezing.

Enrollment: 61 patients

Sex: All

Ages: 50+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Being diagnosed with idiopathic Parkinson's disease
• Healthy individuals who do not have musculoskeletal disease or any neurological disease that may affect assessments
• Older than 50 years old
• Volunteer to participate in the study
• Grade 1-3 on the Modified Hoehn-Yahr Scale
• To have a score above 24 in the Standardized Mini Mental Test
• To have a hemogram follow-up in the last 1 month before the date of participation in the study.
• Being able to walk independently on flat ground

Exclusion criteria

• Having an additional or psychiatric disease other than Parkinson's disease
• Lack of cooperation
• Presence of orthopedic problems (such as fractures, osteoporosis, osteomyelitis)

Trial design

61 participants in 2 patient groups

Parkinson's Patients with Motor Freezing

Description:

Individuals with Parkinson's Disease with motor freezing were included in this group.

Treatment:

Diagnostic Test: Assessment

Parkinson's Patients Without Motor Freezing

Description:

Individuals with Parkinson's Disease without motor freeze were included in this group.

Treatment:

Diagnostic Test: Assessment