Comparison of Blood Loss Between Cemented and Uncemented Femoral Stems in Anterior Total Hip Arthroplasty (FEMFIX)

Clinique du Pré

Status: Not yet enrolling

Conditions: Total Hip Arthroplasty (THA)

Treatments: Procedure: Total hip replacement with cemented fixation; Procedure: Total hip replacement with non-cemented fixation

Study type: Interventional

Funder types: Other

Identifiers

NCT07492212

2025-61-PRM

Details and patient eligibility

About

Total hip arthroplasty (THA) yields excellent results. To perform the procedure, the surgeon must make certain decisions, including the choice of fixation method for the femoral implant.

This surgery, considered to carry a risk of bleeding, therefore exposes the patient :

• to complications: heart attacks, strokes...
• to mortality
• to transfusion: specific risks, cost, length of hospital stay
• to anemia: fatigue, longer recovery time The influence of the femoral fixation method on bleeding and blood loss is often debated, but the literature on the subject is very limited.

Our hypothesis is that the method of femoral fixation in THA influences bleeding and blood loss, with a benefit for cemented fixations.

Enrollment: 86 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patient needed a total hip arthroplasty

Exclusion criteria

• Previous surgery on the affected hip
• Preoperative anemia
• Femoral neck fracture
• Patient with a contraindication to tranexamic acid
• Pregnant or breastfeeding patient

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

86 participants in 2 patient groups

Cemented fixation

Experimental group

Description:

Total hip replacement with cemented fixation

Treatment:

Procedure: Total hip replacement with cemented fixation

Non-cemented fixation

Active Comparator group

Description:

Total hip replacement with non-cemented fixation

Treatment:

Procedure: Total hip replacement with non-cemented fixation