Comparison of Blood Pressure Lowering Effect Between Fimasartan and Losartan

Chuncheon Sacred Heart Hospital

Status and phase: Unknown; Phase 4

Conditions: Hypertension

Treatments: Drug: Losartan; Drug: Fimasartan

Study type: Interventional

Funder types: Other

Identifiers

NCT02958631

CEFILONE Study

Details and patient eligibility

About

Comparison of blood pressure lowering effect between Fimasartan and Losartan in the hypertensive patient during night and early morning time

Enrollment: 40 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subject don't have Anti-hypertensive drug or who stop Anti-hypertensive drug during 2 weeks
• Office BP: over siSBP 140mmHg or si DBP 90mmHg
• 24hr ABPM: SBP 130mmHg or DBP 80mmHg (24 hour Average)

Exclusion criteria

• Pregnant, trying to become pregnant or breast feeding
• Subject has Secondary Hypertension
• White coat Blood Pressure (Normal result of 24 hour ABPM)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

Fimasartan

Experimental group

Description:

Fimasartan 60mg, QD

Treatment:

Drug: Fimasartan

Losartan

Active Comparator group

Description:

Losartan 50mg, QD

Treatment:

Drug: Losartan