Comparison of Bowel Cleansing Methods for Colonoscopy in Hospitalized Patients (PEG)

Kangbuk Samsung Hospital

Status: Unknown

Conditions: Intestine; Complaints

Study type: Observational

Funder types: Other

Identifiers

NCT01528098

PEGPD

Details and patient eligibility

About

The purpose of this study is to compare two regimens of polyethylene glycol(PEG) plus bisacodyl versus PEG alone for bowel preparation in hospitalized patients.

Full description

Inadequate bowel preparation may lead to a longer colonoscopy, and to an inability to identify lesions. PEG can provide a rapid orthograde peroral approach to colonic lavage without producing significant fluid or electrolyte changes. Thus PEG is now commonly used for bowel preparation. However, large amounts and unsatisfactory taste of PEG solution are generally poorly tolerated, especially in hospitalized patients who had comorbidity and restricted ambulation. Recently, a new PEG-based bowel cleansing agents became available. It combines PEG with a high dose of ascorbic acid or bisacodyl. Although many studies reported the efficacy of these combined solution for colonoscopy, but efficacy in hospitalized patients was under-recognized.

Enrollment: 600 estimated patients

Sex: All

Ages: 20 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Hospitalized patients for colonoscopy

Exclusion criteria

• age under 20 years or over 80 years
• major psychiatric illness
• known allergy to PEG
• serious condition- severe cardiac, renal, or metabolic diseases
• partial colon resection
• current acute exacerbation of chronic inflammatory bowel disease
• functional constipation defined by Rome III diagnostic criteria

Trial design

600 participants in 2 patient groups

PEG plus bisacodyl

Description:

Those who taken PEG 4L + bisacodyl 10mg

PEG 4L

Description:

Those who taken PEG 4L alone