Comparison of Brain Network Activation (BNA™) Analysis, Clinical Symptoms and Neuro-cognitive Performance in Concussed Children and Young Adults

ElMindA

Status

Completed

Conditions

Traumatic Brain Injury

Study type

Observational

Funder types

Industry

Identifiers

NCT01532271

ELM-01

Details and patient eligibility

About

The use of Event Related Potentials (ERP) and neurocognitive performance in patients following concussion has been examined previously in small cohorts and relatively long after concussion occurred. However, little is known about the immediate changes in brain activity in specific brain regions and connectivity across them associated with performance on specific neurocognitive tests following a concussion, and the subsequent changes over time. The proposed study will provide initial evidence for the feasibility of an ERP based biomarker for concussion reflecting temporal and spatial changes in brain activity as well as brain functional connectivity associated with concussion.

Enrollment

151 patients

Sex

All

Ages

14 to 27 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Aged 14-27 years
Arm 1 only (Concussed): Over 2 days and below 10 days post-concussion (sports-related)
Currently symptomatic
Willingness to participate and able to give informed assent (child) and/or consent (parent for minors or adult 18+ years of age for self)

Exclusion criteria