Comparison of Brain Volumes Measured by 2D USG and MRI

Ankara City Hospital

Status: Unknown

Conditions: Central Nervous System Vulnerabilities in Preterm Infants

Treatments: Other: Cranial MRI

Study type: Observational

Funder types: Other

Identifiers

NCT04190017

2019512-1

Details and patient eligibility

About

Cranial USG is simple and easy method to assess preterm infant brain. Some studies showed that brain volumes of preterm infants could be calculated by measurement of 2D distances. Our aim in this study was to compare brain volume obtained by USG and MRI.

Full description

All preterm infants less than 32 weeks of gestational age undergo cranial USG examination routinely at least, in the first week of life, at the end of first month and corrected age 36 weeks and 40 weeks. We will performa all USG mesurements with measureing intracranial hegiht, anteroposterior diameter, biparietal diamater, ventriccular height, thalamo-occipital distance and ventricular index. We will calculate the brain volume as a spheric geometric shape than we will calculate two ventricles as conical shapes. Absolute brain volume will be calculating by substracting two ventricles from total brain volume. At 40 weeks of age we will perform a cranial MRI to show exact brain volume and we will ccompare two different methods.

Enrollment: 25 estimated patients

Sex: All

Ages: 1 day to 3 months old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All preterm infants under 32 weeks of gestational age and birth weight between 800-1200 grams
• Born in our hospital
• Alive during discharge

Exclusion criteria

• congenital anomalies
• cranial bleeding
• early death