Comparison of Bupivacaine and Exparel for Carpal Tunnel Release

University of Pittsburgh

Status: Withdrawn

Conditions: Pain After Carpal Tunnel Release

Treatments: Drug: Bupivacaine; Drug: Exparel

Study type: Interventional

Funder types: Other

Identifiers

NCT02141178

PRO14040418

Details and patient eligibility

About

Carpal tunnel syndrome is one of the most common surgeries performed per year in the United States, accounting for over 600,000 surgeries. The procedure is commonly performed under light sedation and local anesthesia. Bupivicaine, a long acting local anesthetic, has been used to allow extended pain relief for 8-10 hours after carpal tunnel release. Exparel, a liposomal bupivicaine formulation, has been documented to provide pain relief for up to 72 hours post-operatively. By decreasing post-operative pain through the use of a long-acting local anesthetic, the use of narcotic pain medications may be decreased and patient satisfaction scores may increase.

The purpose of this study is to prospectively compare bupivicaine and liposomal bupivicaine with respect to post-operative pain control, narcotic usage, and patient satisfaction after carpal tunnel release.

Sex: All

Ages: 18 to 89 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with carpal tunnel syndrome undergoing surgery

Exclusion criteria

• Non english speaking
• Allergy to bupivacaine or exparel

Trial design

0 participants in 2 patient groups

Bupivacaine

Active Comparator group

Description:

Patients will received 0.5% Bupivacaine subcutaneously for local anesthesia during surgery

Treatment:

Drug: Bupivacaine

Exparel

Experimental group

Description:

Patients will received Exparel subcutaneously for local anesthesia during surgery

Treatment:

Drug: Exparel