Comparison of Chen's U-suture Technique with Duct-to-Mucosa Anastomosis and Invagination Pancreaticojejunostomy After Pancreaticoduodenectomy

Chen Xiaoping

Status: Completed

Conditions: Pancreaticoduodenectomy

Treatments: Procedure: Duct-to-Mucosa; Procedure: Chen's U-suture technique; Procedure: invagination

Study type: Observational

Funder types: Other

Identifiers

NCT06863389

Chen'sUsuture1

Details and patient eligibility

About

Data of patients treated with pancreaticoduodenectomy in 21 hospitals from January 2014 to December 2019 were retrospectively collected and classified to Chen's group, duct-to-mucosa group and invagination group according to different pancreaticojejunostomy. Propensity score matching analysis was performed to balance the baseline differences among three groups. The surgical outcomes were compared. Independent risk factors for postoperative pancreatic fistula were confirmed by logistic regression analysis, and subgroup analysis was also conducted.

Enrollment: 5,788 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• open pancreaticoduodenectomy
• Chen's U-suture technique or invagination or duct-to-mucosa anastomosis

Exclusion criteria

• missing data

Trial design

5,788 participants in 3 patient groups

Chen's group

Description:

performing pancreaticojejunostomy by using Chen's U-suture technique

Treatment:

Procedure: Chen's U-suture technique

Invagination group

Description:

performing pancreaticojejunostomy by using invagination method

Treatment:

Procedure: invagination

Duct-to-Mucosa group

Description:

performing pancreaticojejunostomy by using duct-to-mucosa method

Treatment:

Procedure: Duct-to-Mucosa