COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Inherited Retinal Disease (COCO-IRD)

University of Wisconsin (UW)

Status

Enrolling

Conditions

Retinal Disease

Treatments

Device: Optos imaging

Device: Clarus imaging

Device: Spectralis FAF imaging

Study type

Interventional

Funder types

Other

Identifiers

NCT06380075

Protocol Version 3/22/24 (Other Identifier)

2024-0480

SMPH/OPHTHAL&VIS SCI/GEN (Other Identifier)

A536000 (Other Identifier)

Details and patient eligibility

About

The goal of this research study is to compare two ultrawide field cameras to the gold standard imaging system to evaluate the back of the eye. The main question it aims to answer is the same results and information can be acquired from all of the cameras for evaluating and monitoring inherited retinal diseases (IRDs).

Participants will:

undergo pupillary dilation
have photographs taken of the inside of the eyes using three different cameras

Enrollment

50 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Participants 18 years and older with a clinical and/ or genetic diagnosis of IRD recruited either from the clinic and/or the Inherited Ocular Disease Registry to participate in this trial
Participants that are willing to participate as evidenced by signing the written informed consent

Exclusion criteria

Presence of ocular conditions other than an IRD which may affect the quality of ocular imaging including but not limited to advanced cataracts, corneal disorders, nystagmus, vitreous hemorrhage, or poor dilation
Presence of ocular conditions other than an IRD which may affect interpretation of retinal imagining including but not limited to epiretinal membrane, choroidal neovascular membrane, or macular scarring
Patients with advanced IRDs who are unable to fixate for imaging
Patients unable to tolerate ocular imaging
Patients who do not wish to participate