Comparison of Cold Biopsy Forceps vs Cold Snare for Diminutive Colorectal Polyp Removal (BIOPANS)

Gabriel RAHMI

Status: Completed

Conditions: Colorectal Polyps

Treatments: Procedure: Polypectomy of diminutive colorectal polyps will be performed by CSP; Procedure: Polypectomy of diminutive colorectal polyps will be performed by CBF

Study type: Interventional

Funder types: Other

Identifiers

NCT04727918

SFED 105

Details and patient eligibility

About

European guidelines recommend the use of cold snare polypectomy (CSP) for removal of diminutive colorectal polyps (DCP)(5 mm or less). However, for DCP < 4 mm cold biopsy forceps (CBF) may be optional. Moreover, CBF remains the endoscopist's technique of choice for polyp resection and CSP is associated with a failure of specimen retrieval for histology in up to 6.8% of cases. In this study, the investigators aimed to compare the efficacy of CSP with CBF for removal of DCP in routine colonoscopy

Enrollment: 126 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Routine colonoscopy
• Patient older than 18 years
• at least one polyp measuring ≤ 5 mm

Exclusion criteria

• inflammatory bowel disease
• polyposis syndrome, pregnancy
• inability to provide informed consent

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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126 participants in 2 patient groups

Cold biopsy forceps (CBF)

Active Comparator group

Description:

Patients will be allocated to the CBF arm after randomization (1:1)

Treatment:

Procedure: Polypectomy of diminutive colorectal polyps will be performed by CBF

Cold snare polypectomy (CSP)

Active Comparator group

Description:

Patients will be allocated to the CSP arm after randomization (1:1)

Treatment:

Procedure: Polypectomy of diminutive colorectal polyps will be performed by CSP