Comparison of Compressed Continuous Suture and Conventional Suture in Pterygium Surgery

Tianjin Eye Hospital

Status: Enrolling

Conditions: Primary Pterygium

Treatments: Procedure: Compression continuous suture with suture crimping; Procedure: Conventional Suture with suture crimping

Study type: Interventional

Funder types: Other

Identifiers

NCT07244276

zhangyi2025

Details and patient eligibility

About

To compare the advantages and disadvantages of continuous suture with suture and conventional Suture in primary pterygium surgery for autologous conjunctival graft fixation

Full description

Pterygium is an abnormal fibrovascular tissue hyperplasia disease that occurs in the conjunctiva. The pterygium tissue can break through the limbus of the corneosclera and grow into the cornea, causing a foreign body sensation in the eyes, astigmatism, decreased vision, and even restricted eye movement. The purpose of surgical treatment for pterygium is not only to remove the diseased tissue, but more importantly, to reduce the recurrence of pterygium after surgery. Pterygium excision combined with simple autologous conjunctival transplantation is currently the most commonly used method for treating pterygium. The recurrence rate after autologous conjunctival epithelial tissue transplantation can be reduced to 5% to 30%.

As heterogenic substances, sutures can irritate the ocular surface, aggravate postoperative inflammatory reactions and conjunctival edema or hemorrhage, delay the repair of corneal wound epithelium, lead to abnormal ocular surface function, intensify postoperative discomfort, and induce hypertrophic granuloma or cysts, etc. Moreover, these adverse reactions can also induce the recurrence of pterygium (0-26%). In addition, the longer the time interval between suture removal, The greater the difficulty of removal, the more likely some of the knots may be completely buried under the conjunctiva. Therefore, in order to alleviate the adverse reactions caused by sutures and further simplify the operation of pterygium excision surgery, many attempts have been made at home and abroad to improve and innovate the method of graft fixation.

Enrollment: 40 estimated patients

Sex: All

Ages: 30 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Diagnosis of primary pterygium according to diagnostic criteria;
2. The pterygium head invades the cornea by 2-5mm;
3. The patient agrees to the surgical treatment and signs the surgical consent form.

Exclusion criteria

1. History of previous eye surgery;
2. Have active ocular inflammatory lesions;
3. recurrent and pseudopterygium;
4. The patient refuses surgery or is unable to have regular follow-ups

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Factorial Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

Continuous suture group

Other group

Description:

Pterygium excision combined with autologous conjunctival transplantation was performed

Treatment:

Procedure: Compression continuous suture with suture crimping

Intermittent suture group

Other group

Description:

Pterygium excision combined with autologous conjunctival transplantation was performed

Treatment:

Procedure: Conventional Suture with suture crimping