Comparison of Conventional and Cooled Radiofrequency Ablation in Knee Osteoarthritis

Gaziler Physical Medicine and Rehabilitation Education and Research Hospital

Status: Enrolling

Conditions: Knee Osteoarthritis

Treatments: Device: Radiofrequency ablation

Study type: Interventional

Funder types: Other

Identifiers

NCT06863181

AEŞH-EK-2025-064

Details and patient eligibility

About

The aim of this study was to examine and compare the effects of conventional and cooled radiofrequency ablation on pain and disability levels in patients with knee pain resistant to other treatments due to knee osteoarthritis.

Enrollment: 26 estimated patients

Sex: All

Ages: 50 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Knee pain lasting more than 6 months

• Age between 50 and 80

• Diagnosis of radiographically proven grade III or IV knee osteoarthritis according to the Kellgren-Lawrence Grading Scale, marked narrowing of the medial compartment of the tibiofemoral joint space

• Presence of pain resistant to conservative treatment

  • Exercise
  • Physical therapy agents
  • Use of oral anti-inflammatory agents

Exclusion criteria

• History of trauma to the knee area
• History of knee surgery
• Presence of systemic inflammatory disease affecting the knee joint
• Presence of peripheral neuropathy or radiculopathy
• Pregnancy
• Hemodynamic instability
• Presence of skin or soft tissue infection at the injection site
• Refusal to participate in the study
• Presence of acute knee pain with accompanying inflammatory findings
• Presence of a serious psychiatric disorder or neurological disease Having received an intra-articular injection within the last 3 months

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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26 participants in 2 patient groups

Conventional Radiofrequency Ablation

Active Comparator group

Description:

Conventional radiofrequency ablation with fluoroscopy

Treatment:

Device: Radiofrequency ablation

Cooled Radiofrequency Ablation

Experimental group

Description:

Cooled radiofrequency ablation with ultrasound

Treatment:

Device: Radiofrequency ablation