Comparison of Critical Flicker Fusion Versus Automated Visual Fields in the Detection of Early Glaucoma

Northwell Health

Status: Completed

Conditions: Glaucoma

Study type: Observational

Funder types: Other

Identifiers

NCT01076114

09-320

Details and patient eligibility

About

The purpose of this study is to evaluate if critical flicker fusion is a more reliable method for detection of early glaucoma compared to automated visual fields in comparison to subjects without evidence of glaucoma or optic nerve disease.

Full description

Our hypothesis is that critical flicker fusion (CFF) is a more reliable method for detection of early glaucoma compared to automated visual fields in comparison to subjects without evidence of glaucoma or optic nerve disease. We aim to evaluate the structure of the optic nerve and compare it to results of visual fields and CFF. The CFF will also be correlated with intraocular pressure (IOP) measurements to observe if it may be more closely related than visual fields. This may become an additional tool to detect glaucoma in those with unreliable visual fields or who are unable to perform a visual field from physical or mental limitations.

Enrollment: 58 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion:

• Glaucoma Suspects:
• Abnormal optic disc appearance with increased cup to disc ratio, or
• Increased intraocular pressure >21 in either eye
• Control Subjects:
• Normal appearing optic discs
• Normal intraocular pressure (<21)

Exclusion:

• Other ocular pathology
• History of seizures or epilepsy

Trial design

58 participants in 2 patient groups

Control

Description:

Patients with no evidence of glaucoma or as a suspect with normal intraocular pressure, normal cup to disc ratio with no other ocular pathology and a normal ophthalmic exam.

Glaucoma Suspect

Description:

Patients with abnormal cup to disc ratio or increased intraocular pressure (\>21mm/Hg) with an otherwise normal ophthalmic exam.