Comparison of Cruciate Retaining and Posterior Stabilized Total Knee Arthroplasty

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Ewha Womans University

Status

Completed

Conditions

Arthropathy of Knee Joint
Osteoarthritis, Knee

Treatments

Procedure: Total knee replacement with cruciate substituting femoral component
Procedure: Total knee replacement with cruciate retaining femoral component

Study type

Interventional

Funder types

Other

Identifiers

NCT06124651
tka_cr_ps

Details and patient eligibility

About

Several authors and large registries have suggested the potential for an increased risk of all-cause revision with the use of posterior cruciate-substitution (PS) total knee arthroplasty (TKA). The purpose of the current study was to compare posterior cruciate retaining (CR) and PS implants with respect to the functional and radiographic results, prevalence of osteolysis, revision rates and survivorship.

Full description

The supremacy debate between posterior cruciate-retaining (CR) and posterior stabilized (PS) total knee arthroplasty (TKA) has now entered into the 4th decade. Multiple research studies have investigated CR and PS TKAs on the basis of kinematic, clinical, radiographic, and survivorship analysis. Despite arguments in favor of CR or PS TKA designs, several short or mid-term studies have shown no difference in functional outcomes between these two designs. Considering the fact that CR and PS TKA fare equally at short-term and mid-term, the decision to select either design should depend on their long-term survivorship. There have been few long-term survivorship analysis that have directly compared CR and PS TKAs with aseptic revision for any reason as the end point. These long-term studies of CR and PS TKA have been done independently. A comparison of the results in the same patients eliminates the variability that is introduced by differences in gender, age, weight, comorbidity, bone quality, and activity level and allows for a meaningful comparison of the impact of fixation on the outcome of TKA. However, variability in terms of the preoperative severity of arthritis cannot be eliminated because of the design on both sides is rarely identical. The purpose of this study was to identify differences in implant survivorship between CR and PS TKAs in patients with osteoarthritis who were younger than 65 years of age and CR implant in one knee and PS implant in the other.

Enrollment

300 patients

Sex

All

Ages

25 to 99 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • End-stage osteoarthritis of the knee joint requiring total knee arthroplasty with bilateral disease

Exclusion criteria

  • Inflammatory disease
  • patient with other Lower extremity disease which may affect functional outcome
  • Neurologic disease effecting patients lower extremity
  • Revision surgery
  • Patient not medically cleared for bilateral surgery

Trial design

300 participants in 2 patient groups

CR knee
Active Comparator group
Description:
This type of total knee arthroplasty retains the posterior cruciate ligament.
Treatment:
Procedure: Total knee replacement with cruciate retaining femoral component
PS knee
Active Comparator group
Description:
This type of total knee sacrifices the posterior cruciate ligament and cam and post mechanism replaces its function.
Treatment:
Procedure: Total knee replacement with cruciate substituting femoral component

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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