Comparison of CTI Ablation Prior to or After LA Ablation for AF

NYU Langone Health

Status and phase: Completed; Phase 3

Conditions: Atrial Fibrillation

Treatments: Procedure: CTI ablation Timing

Study type: Interventional

Funder types: Other

Identifiers

NCT02325778

10-01007

Details and patient eligibility

About

This study is designed to determine if CTI prior to CPVA/PVI/Linear Lesions/Fractionation results in reduced left atrial ablation lesion sets prior to restoration of sinus rhythm in patients with long standing persistent atrial fibrillation in the absence of antiarrhythmic drug therapy compared to CTI after CPVA/PVI/Linear Lesions/Fractionation.

Enrollment: 132 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• continuous/persistent atrial fibrillation

Exclusion criteria

• age<18
• congenital heart disease
• pacemaker or ICD implant
• previous ablation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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132 participants in 2 patient groups

CTI First

Experimental group

Description:

CTI ablation prior to left atrial ablation

Treatment:

Procedure: CTI ablation Timing

CTI second

Experimental group

Description:

CTI ablation after left atrial ablation

Treatment:

Procedure: CTI ablation Timing